Apixaban ≥98%, crystalline solid
Supplier: Cayman Chemical
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Danger
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Synonyms:
BMS56224701, 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide, 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM).
In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model of aortic heterotopic valve replacement. Formulations containing apixaban have been used to prevent blood clot formation in patients with atrial fibrillation.
Formula:
C₂₅H₂₅N₅O₄ MW: 459,5 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD11977295 CAS Number: 503612-47-3 |
Specification Test Results
Purity | ≥98% |
λmax (UV/Vis) | 281 nm |
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