(R)-(-)-2-Amino-5-phosphonopentanoic acid ≥95%

Supplier: Cayman Chemical
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Synonyms: D-2-Amino-5-phosphonovaleric acid, (R)-2-Amino-5-phosphonopentanoic acid, D-AP5

14539-10 14539-50 14539-100 14539-5
CAYM14539-10EA 168 GBP
CAYM14539-10 CAYM14539-50 CAYM14539-100 CAYM14539-5
(R)-(-)-2-Amino-5-phosphonopentanoic acid ≥95%
(R)-(-)-2-Amino-5-phosphonopentanoic acid

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd=1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors.


D-AP5 is the active (−)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.

Formula: C₅H₁₂NO₅P
MW: 197,127 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00078839
CAS Number: 79055-68-8

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Specification Test Results

Purity ≥95%

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