Mouse recombinant IL-17A (from E. coli)

Supplier: Shenandoah Biotechnology

200-59-1MG 200-59-25UG 200-59-500UG 200-59-5UG
SHBT200-59-1MGEA 2980 GBP
SHBT200-59-1MG SHBT200-59-25UG SHBT200-59-500UG SHBT200-59-5UG
Mouse recombinant IL-17A (from E. coli)
Proteins and Peptides

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes.


  • Produced from genetically modified E. coli
  • Dimeric protein contains 134/268 amino acids
  • Human, mouse, and rat IL-17A show activity on mouse cells


IL-17A acts through its receptor and IL-17R is to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites.


Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis.


Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.


Caution: This product is for research use only and is not for use in humans.

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