Mouse recombinant IL-17A (from E. coli)
Supplier: Shenandoah Biotechnology
Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes.
- Produced from genetically modified E. coli
- Dimeric protein contains 134/268 amino acids
- Human, mouse, and rat IL-17A show activity on mouse cells
IL-17A acts through its receptor and IL-17R is to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites.
Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...