4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulphonic acid dipotassium salt ≥98%, crystalline solid fluorescent dye
Supplier: Cayman Chemical
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Synonyms:
Bis-ANS
bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation. Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.
- Emission 523 (free), 496 (bound) nm
- Excitation 390 (free), 484 (bound) nm
- λmax 222, 275, 395 nm
bis-ANS has an excitation maxima of 390 nm. It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima of 484-496 nm. bis-ANS has been used to label mechanically damaged neurons in acute brain slices. It also potently inhibits microtubule assembly.
Formula:
C₃₂H₂₂K₂N₂O₆S₂ MW: 672,85 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00011592 CAS Number: 65664-81-5 |
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