Tris(hydroxymethyl)aminomethane (TRIS, Trometamol), Certipur® Reag. USP, Reag. Ph. Eur. volumetric standard, secondary reference material for acidimetry, traceable to NIST Standard Reference Material (SRM), Supelco®

Supplier: Merck

Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol(tris), Tromethamine, Tris(hydroxymethyl)methylamine, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Trizma(R) base, TRIS base, THAM

M-Clarity™ quality level = MQ100

1.02408.0080 1.02408.0083
1.02408.0080EA 150 GBP
1.02408.0080 1.02408.0083
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol), Certipur® Reag. USP, Reag. Ph. Eur. volumetric standard, secondary reference material for acidimetry, traceable to NIST Standard Reference Material (SRM), Supelco®
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)

Tris(hydroxymethyl)aminomethane volumetric standard, secondary reference material for acidimetry, traceable to NIST Standard Reference Material (SRM)


  • 10.2 - 10.6 (6 g/l, H₂O, 20 °C)


Merck have introduced into the range of Certipur® standards some packs with additional technology - Supelco® SmartTitrants that use an RFID tag to provide a seamless data transfer between the smart titrator and the RFID tag on the label of the bottle of titrant. It will ensure that all information needed for method execution, result calculation and documentation is transferred to the titrator equipped with this technology. MettlerToledo Compact and Excellence titrators include this technology. Please see ordering table below for packs with RFID tag.

Formula: NH₂C(CH₂OH)₃
MW: 121,14 g/mol
Boiling Pt: 219…220 °C (13,3 hPa)
Melting Pt: 171…172 °C
Density: 1,35 g/cm3 (23 °C)
Storage Temperature: Ambient
MDL Number: MFCD00004679
CAS Number: 77-86-1
EINECS: 201-064-4
Merck Index: 13,09842
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Specification Test Results

Solubility 800 g/l (20 °C)
Melting Point 171.2 °C
Molar Mass 121.1 g/mol
Bulk Density 840 kg/m3
Boiling Point 219 - 220 °C (13.3 hPa)
Vapor Pressure 0.000267 Pa (20 °C)
Density 1.353 g/cm3 (23 °C)
pH 10.2 - 10.6 (6 g/l, H2O, 20 °C)

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