Glycine ≥98%, powder

Supplier: MP Biomedicals

Synonyms: Aminoacetic acid, Glycocoll, H-Gly-OH

0210057025 02100570.5 0210057001 0210057005
ICNA0210057025EA 1290 GBP
ICNA0210057025 ICNA02100570.5 ICNA0210057001 ICNA0210057005
Glycine ≥98%, powder
Glycine

Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.


Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.


It is a non-chiral amino acid that can be synthesised in the body from the amino acid serine by Serine Hydroxy methyltransferase.


Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.


Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.

Formula: NH₂CH₂COOH
MW: 75,07 g/mol
Boiling Pt: 181 °C (1013 hPa)
Melting Pt: 83 °C
Density: 1,64 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00008131
CAS Number: 56-40-6
EINECS: 200-272-2
Merck Index: 13,04504
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Specification Test Results

Synonyms Amino acetic acid; Gly; Amino ethanoic acid; Glycocoll
Form Powder
Storage Store at room temperature (15 to 30 °C)
Isoelectric Point 6,06
Loss on Drying ≤0,5%
pka for the α carboxyl group: 2,35; and for the α amino group: 9,78 at 25 °C

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