Glycine ≥98%, powder
Supplier: MP Biomedicals
Synonyms:
Aminoacetic acid, Glycocoll, H-Gly-OH
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.
Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.
It is a non-chiral amino acid that can be synthesised in the body from the amino acid serine by Serine Hydroxy methyltransferase.
Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.
Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.
Formula:
NH₂CH₂COOH MW: 75,07 g/mol Boiling Pt: 181 °C (1013 hPa) Melting Pt: 83 °C Density: 1,64 g/cm³ (20 °C) Storage Temperature: Ambient |
MDL Number:
MFCD00008131 CAS Number: 56-40-6 EINECS: 200-272-2 Merck Index: 13,04504 |
Specification Test Results
Synonyms | Amino acetic acid; Gly; Amino ethanoic acid; Glycocoll |
Form | Powder |
Storage | Store at room temperature (15 to 30 °C) |
Isoelectric Point | 6,06 |
Loss on Drying | ≤0,5% |
pka | for the α carboxyl group: 2,35; and for the α amino group: 9,78 at 25 °C |
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