PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt) ≥97%
Supplier: Cayman Chemical
Synonyms:
1-(1,2R-dioctanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt, DOPI-4,5-P2, Phosphatidylinositol-4,5-bisphosphate C-8
The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.
- Formulation: A lyophilized powder
- Storage: -20°C
- Stability: ≥ 1 year
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