Prostaglandin A1-biotin solution ≥95% in ethanol
Supplier: Cayman Chemical
Prostaglandin A1 (PGA1) is one of the cyclopentenone prostaglandins, with antimitotic and antiproliferative effects.
- N-9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oyl-N'-biotinoyl-1,6-diaminopentane
- Purity of ≥95%
- A solution in ethanol
The activity of the compounds in this class, which includes prostaglandins in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical (i.e., non-G protein-coupled receptor) pathways. PGA1-biotin is an affinity probe which allows PGA1 to be detected through an interaction with the biotin ligand. PGA1-biotin was designed to allow PGA1 to be detected in complexes with nucleic acid or protein binding partners. Used in the general elucidation of the mechanism of action of the cyclopentenone prostaglandins.
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