Fumonisin B1 ≥95%, crystalline solid
Supplier: Cayman Chemical
Fumonisin B₁ is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)
Fumonisin B₁ attenuates the response of P388D1 cells to PAF and LPS by inhibiting ceramide formation. It also blocks the apoptotic response of HaCaT cells to the antiproliferative drug hexadecylphosphocholine, again through inhibition of ceramide production. Incubation of Swiss 3T3 cells with fumonisin B₁ results in both an altered cell morphology due to disruption of axonal growth and a decrease in cell proliferation
Formula:
C₃₄H₅₉NO₁₅ MW: 721,838 g/mol |
MDL Number:
MFCD00133349 CAS Number: 116355-83-0 |
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