Anti-ACTA2 Rat Monoclonal Antibody (Biotin) [clone: 1A4]

Supplier: Biotium
BNCB0665-500 BNCB0665-100
BNCB0665-500EA 538 GBP
BNCB0665-500 BNCB0665-100
Anti-ACTA2 Rat Monoclonal Antibody (Biotin) [clone: 1A4]
Antibodies
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

Type: Primary
Antigen: ACTA2
Clonality: Monoclonal
Clone: Clone 1A4
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Baboon, Cat, Chicken, Cow, Dog, Goat, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
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