Anti-PTPRC Mouse Monoclonal Antibody (CF660R) [clone: 2B11]

Supplier: Biotium
BNC610470-500 BNC610470-100
BNC610470-500EA 538 GBP
BNC610470-500 BNC610470-100
Anti-PTPRC Mouse Monoclonal Antibody (CF660R) [clone: 2B11]
Antibodies
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: 2B11
Conjugation: CF660R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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