Anti-CD55 Mouse Monoclonal Antibody (Biotin) [clone: 143-30]

Supplier: Biotium

BNCB0179-500 BNCB0179-100
BNCB0179-500EA 510 GBP
BNCB0179-500 BNCB0179-100
Anti-CD55 Mouse Monoclonal Antibody (Biotin) [clone: 143-30]
Antibodies
Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Type: Primary
Antigen: CD55
Clonality: Monoclonal
Clone: 143-30
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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