Minocycline hydrochloride, yellow powder
Supplier: MP Biomedicals
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Warning
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Synonyms:
(4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride, Minocycline HCl
Minocycline hydrochloride (INN) is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type.
Minocycline inhibits endothelial cell proliferation and angiogenesis.
Minocycline is active against streptococci,enterobacteria, and some mycobacteria, and also against such species as Staphylococcus aureus, Neisseria meningitidis, Acinetobacter, Bacteroides, Haemophilus, and Nocardia.
Minimum inhibitory concentrations (MIC) can range from 0,06 to 1 μg/ml for the most sensitive organisms, and from 4 to 12,5 μg/ml for moderately sensitive organisms.
Soluble in methanol and aqueous solutions of alkali hydroxides and carbonates.
Formula:
C₂₃H₂₇N₃O₇ MW: 493,94 g/mol |
MDL Number:
MFCD00083669 CAS Number: 13614-98-7 |
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