Propyl-3,4,5-trihydroxybenzoate, off-white powder

Supplier: MP Biomedicals
Warning

Synonyms: Gallic acid propyl ester, Propyl gallate, Propyl 3,4,5-trihydroxybenzoate, Progalline P, N-Propyl gallate

0210274750 0210274780 0210274790
ICNA0210274750EA 35.5 GBP
ICNA0210274750 ICNA0210274780 ICNA0210274790
Propyl-3,4,5-trihydroxybenzoate, off-white powder
Propyl 3,4,5-trihydroxybenzoate

n-Propyl gallate is an ester formed by the condensation of gallic acid and propanol. This antioxidant has been added to foods containing oils and fats to prevent oxidation.


n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.


An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0,25 µM when it was combined with copper concentrations at 5 µM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0,5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.


Soluble in ethanol (50 mg/ml).


Caution: Research Use Only (RUO).

Formula: C₁₀H₁₂O₅
MW: 212,2 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00002196
CAS Number: 121-79-9

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Specification Test Results

Identity Test Passes
FTIR Conforms to Standard
Melting Point 140 - 150 °C

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