CCVJ ≥95%
Supplier: Cayman Chemical
Synonyms:
9-(2-Carboxy-2-cyanovinyl)julolidine, (E)-2-Cyano-3-(1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinolin-9-yl)acrylic acid
CCVJ is a fluorescent molecular rotor characterised by low background fluorescence, low fluorescence anisotropy, and good water solubility. Fluorescent molecular rotors are molecules whose fluorescence is inversely proportional to its intramolecular rotation.
The intramolecular rotation of these probes, and hence their fluorescence, depends on the immediate microenvironment of the probe. As a result, fluorescent molecular rotors are used to evaluate changes in solution and membrane viscosity, polymerisation or aggregation processes, and protein (un)folding.
Moreover, it has large hydrophobic structures, allowing it to associate in a non-covalent manner with hydrophobic pockets in proteins in solution. It is broadly used to monitor changes in solution and molecular characteristics.
Formula:
C₁₆H₁₆N₂O₂ MW: 268,31 g/mol |
MDL Number:
MFCD00274408 CAS Number: 142978-18-5 |
Specification Test Results
Purity | ≥95% |
Formal Name | 2-cyano-3-(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)-2-propenoic acid |
Formulation | A Crystalline Solid |
λmax | 279, 441 nm |
SMILES | OC(/C(C#N)=C/C1=CC(CCC2)=C(N2CCC3)C3=C1)=O |
InChI Code | 1S/C16H16N2O2/c17-10-14(16(19)20)9-11-7-12-3-1-5-18-6-2-4-13(8-11)15(12)18/h7-9H,1-6H2,(H,19,20)/b14-9+ |
InChI Key | JXENNHTVELFRHV-NTEUORMPSA-N |
Storage | −20 °C |
Shipping | Room temperature in continental US; may vary elsewhere |
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