Paroxetine hydrochloride ≥98%

Supplier: Cayman Chemical

Synonyms: (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride

14998-10 14998-25 14998-100 14998-50
CAYM14998-10EA 82 GBP
CAYM14998-10 CAYM14998-25 CAYM14998-100 CAYM14998-50
Paroxetine hydrochloride ≥98%
Paroxetine hydrochloride

Paroxetine is a phenylpiperidine derivative that potently and selectively inhibits the reuptake of serotonin, blocking the human serotonin transporter with a Ki value of 0,72 nM.


It less effectively blocks the human norepinephrine and dopamine transporters (Ki = 440 and 1,900 nM, respectively). Paroxetine also inhibits, at concentrations in excess of 1 µM, nitric oxide synthase activity in the cytosol of hamster brain. Selective serotonin uptake inhibitors, including paroxetine, are used in cases of depression and anxiety disorder.

Formula: C₁₉H₂₁ClFNO₃
Storage Temperature: Freezer
CAS Number: 78246-49-8

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Specification Test Results

Purity ≥98%
Formal Name (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine, monohydrochloride
Synonyms BRL 29060A
Formulation A Crystalline Solid
λmax 235, 265, 271, 295 nm
SMILES FC1=CC=C([C@H]2[C@H](COC3=CC(OCO4)=C4C=C3)CNCC2)C=C1.Cl
InChI Code 1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1
InChI Key GELRVIPPMNMYGS-RVXRQPKJSA-N
Storage −20 °C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years from the QC date provided on the Certificate of Analysis, when stored properly

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