5-Azacytidine, white powder

Supplier: MP Biomedicals
Danger

Synonyms: Ladakamycin, 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one

0210082150 0210082180 0210082183 0210082191
ICNA0210082150EA 36.6 GBP
ICNA0210082150 ICNA0210082180 ICNA0210082183 ICNA0210082191
5-Azacytidine, white powder
5-Azacytidine

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.


A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes


Soluble in water (50 mg/ml-clear, colorless solution).


Caution: Research Use Only (RUO).

Formula: C₈H₁₂N₄O₅
MW: 244,21 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00006539
CAS Number: 320-67-2

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