5-Azacytidine, white powder
Supplier: MP Biomedicals
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Danger
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Synonyms:
Ladakamycin, 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.
A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes
Soluble in water (50 mg/ml-clear, colorless solution).
Caution: Research Use Only (RUO).
Formula:
C₈H₁₂N₄O₅ MW: 244,21 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00006539 CAS Number: 320-67-2 |
Specification Test Results
Identity Test | Passes |
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