Ascomycin 95%
Supplier: Thermo Scientific
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Warning
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Synonyms:
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
An analog of tacrolimus (FK-506). Ascomycin is an inhibitor of PP2 and it is potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
- White
Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water
Formula:
C₄₃H₆₉NO₁₂ MW: 790 g/mol Boiling Pt: 868 °C Melting Pt: 156…160 °C Flash Pt: >110 °C (230 °F) Storage Temperature: Freezer |
MDL Number:
MFCD06198665 CAS Number: 104987-12-4 |
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