You Searched For: Precolumn Filters and Frits

Precolumn filters are essential for protecting HPLC columns against particulate matter which can accumulate on the column frit, leading to split peaks and high backpressure. Sources of particles include mobile phases (especially when buffers are mixed with organic solvents), leaking pump and injector seals, and samples. Precolumn filters are also useful because changing the column frit is extremely difficult to do without disturbing the column packing, whereas changing the precolumn filter’s frit is easy, providing relatively inexpensive insurance against column damage.

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Precolumn filters, ColumnSaver

Supplier: Merck

Description: Precolumn filter kit has a standard 10-32 fitting and fits direct to most column types without introducing an additional dead volume.

VWR® Hichrom Precolumn Filters

Supplier: Avantor

Description: Placed immediately before the column, the precolumn filter traps particles introduced with the sample. For samples, which may irreversibly absorb onto the column, the use of guard cartridges is strongly recommended.

Avantor® ACE®, UHPLC Pre-Column Filters

Supplier: Avantor

Description: Avantor® ACE® UHPLC pre-column filters made from stainless steel/PEEK provide protection for all UHPLC columns. They offer ultra-low dispersion for maximum compatibility with UHPLC instruments and columns. For use with Waters 'Classic' Acquity® systems, an alternative Waters Acquity® compatible version provides improved performance.

Avantor® ACE®, HPLC Precolumn Filters

Supplier: Avantor

Description: These precolumn filters with PEEK body and stainless steel frit provide protection for analytical and microbore columns. They connect directly to the column without the need for an additional holder.