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Ethidium bromide

Catalog Number: (ICNA04802511)
Supplier: MP Biomedicals
Description: Ethidium bromide(EtBr) has been used extensively to reduce mitochondrial DNA copy number in proliferating cells and most commonly used in nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration (10 μg/mL). Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA.4 Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. A 10mg/mL easy-to-use solution of Ethidium bromide in specially filtered, deionized water which is excellent for nucleic acid electrophoresis and purification applications, eliminates the dust hazard associated with powdered Ethidium bromide and saves time spent on weighing and mixing. Used in the fluorometric detection of double stranded nucleic acids in gel electrophoresis. Also acts as an RNA polymerase inhibitor, and in separation of high molecular weight DNA's. It confers a deep red stain to DNA by acting as an intercalating agent between the starch bases. Subsequent fluorescence techniques enable the extraction and characterization of DNA bands. Biochem/physiol Actions: Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It can also be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.
UOM: 1 * 10 mL
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Ethidium bromide 10 mg/ml in aqueous solution, dark red solution for molecular biology

Supplier: MP Biomedicals
Description: A 10 mg/mL Ready-To-Use solution of EtBr in specially filtered, deionized water.

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Ethidium bromide 10 mg/ml in aqueous solution

Catalog Number: (MOBO15006-10)
Supplier: MO BIO
Description: Ethidium bromide 10 mg/ml in aqueous solution
UOM: 1 * 10 mL

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-MOLEM16559763

Ethidium bromide

Catalog Number: (MOLEM16559763)
Supplier: Molekula
Description: Ethidium bromide
UOM: 1 * 5 g

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-MOLE34277542-25G

Ethidium bromide

Catalog Number: (MOLE34277542-25G)
Supplier: Molekula
Description: Ethidium bromide
UOM: 1 * 25 g

Market Source Item This is a MarketSource item. Additional charges may apply

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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