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Brefeldin A

Description: Brefeldin A
Catalog Number: CAYM11861-25
UOM: 1 * 25 mg
Supplier: Cayman Chemical
Product Image-ACRO297140250

Brefeldin A (natural)

Description: Brefeldin A (natural)
Catalog Number: ACRO297140250
UOM: 1 * 25 mg
Supplier: Thermo Fisher Scientific

MSDS


Image Unavailable-ENZOBMLG4050005

Brefeldin A ≥98% (by TLC)

Description: GEF inhibitor
Catalog Number: ENZOBMLG4050005
UOM: 1 * 5 mg
Supplier: ENZO LIFE SCIENCES

New Product


Image Unavailable-APOSBIB3042-25MG

Brefeldin A

Description: BFA is a macrolide antiobiotic. Disrupts mechanism of Golgi apparatus.
Catalog Number: APOSBIB3042-25MG
UOM: 1 * 25 mg
Supplier: Apollo Scientific
Image Unavailable-J62340.MB

Brefeldin A ≥99%

Description: Brefeldin A ≥99%
Catalog Number: J62340.MB
UOM: 1 * 25 mg
Supplier: Thermo Fisher Scientific

MSDS Certificates


Image Unavailable-203729-1

Brefeldin A, Millipore®

Description: Brefeldin A, Millipore®
Catalog Number: 203729-1
UOM: 1 * 1 mg
Supplier: Merck Millipore (Calbiochem‎)
Image Unavailable-ICNA0219480205

Brefeldin A ≥98%, white powder for molecular biology

Description: Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
Catalog Number: ICNA0219480205
UOM: 1 * 5 mg
Supplier: MP Biomedicals
Image Unavailable-MOLEM49595136

Brefeldin A

Description: Brefeldin A
Catalog Number: MOLEM49595136
UOM: 1 * 5 mg
Supplier: Molekula
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